[HTML][HTML] Deep-learning based analysis of in-vivo confocal microscopy-derived metrics of the corneal nerve whorl in eyes with neuropathic ocular pain and controls
M Soifer, Z Zemborain, S Komai… - … & Visual Science, 2023 - iovs.arvojournals.org
Investigative Ophthalmology & Visual Science, 2023•iovs.arvojournals.org
Purpose: To compare in-vivo confocal microscopy (IVCM) metrics of sub-basal corneal
nerves, immune cells, and neuromas patients with neuropathic ocular pain (NOP) and
controls using deep learning-based automated segmentation and assess the validity of
corneal nerve whorl detection Methods: In-vivo confocal microscopy images of the corneal
whorl were collected from 97 eyes (49 NOP, 48 Controls). Inclusion criteria for neuropathic
ocular pain included Ocular Surface Disease Index (OSDI)> 13, minimal to no ocular surface …
nerves, immune cells, and neuromas patients with neuropathic ocular pain (NOP) and
controls using deep learning-based automated segmentation and assess the validity of
corneal nerve whorl detection Methods: In-vivo confocal microscopy images of the corneal
whorl were collected from 97 eyes (49 NOP, 48 Controls). Inclusion criteria for neuropathic
ocular pain included Ocular Surface Disease Index (OSDI)> 13, minimal to no ocular surface …
Abstract
Purpose: To compare in-vivo confocal microscopy (IVCM) metrics of sub-basal corneal nerves, immune cells, and neuromas patients with neuropathic ocular pain (NOP) and controls using deep learning-based automated segmentation and assess the validity of corneal nerve whorl detection
Methods: In-vivo confocal microscopy images of the corneal whorl were collected from 97 eyes (49 NOP, 48 Controls). Inclusion criteria for neuropathic ocular pain included Ocular Surface Disease Index (OSDI)> 13, minimal to no ocular surface fluorescein staining (less or equal to 1 on NEI scale), and presence of ocular pain.
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