Deficient amygdala habituation to threatening stimuli in borderline personality disorder relates to adverse childhood experiences

E Bilek, ML Itz, G STÖßEL, R Ma, O Berhe, L Clement… - Biological …, 2019 - Elsevier
Background Heightened amygdala response to threatening cues has been repeatedly
observed in borderline personality disorder (BPD). A previous report linked hyperactivation
to deficient amygdala habituation to repeated stimuli, but the biological underpinnings are
incompletely understood. Methods We examined a sample of 120 patients with BPD and
115 healthy control subjects with a well-established functional magnetic resonance imaging
emotional face processing task to replicate the previously reported amygdala habituation …
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