Dealloying‐driven nanoporous metals possess three‐dimensional bicontinuous ligament‐channel structure on the nanoscale, high specific surface area, and good electrical conductivity. Such a unique structure endows nanoporous metals with great potentials as electrocatalysts for fuel cell applications. Herein, we mainly focus upon design and fabrication of a nanoporous metallic electrocatalyst. The compositions, microstructures, and electrocatalytic properties of nanoporous metals could be precisely modulated through compositional design of precursor alloys fordealloying and control over dealloying conditions (solution type, solution concentration, temperature and etching duration, etc.). The nanoporous structure could be tuned from homogeneous to bimodal/nested and even to hierarchical. Besides pure metals, nanoporous binary, ternary, and multicomponent alloys could also be fabricated by the dealloying strategy. Moreover, through underpotential deposition or displacement reaction, nanoporous metals could be further modified or decorated to enhance their electrocatalytic performance. For practical applications in fuel cells, other issues should also be taken into consideration, such as long‐term stability, scale‐up, cost, and so on.