22 天前 - … (PDAC) accounts for over 80% of all kinds of pancreatic cancer and it is known as
one … The tumor stroma ultimately results in desmoplasia and fibrotic responses creating a …

22 天前 - … , and drug resistance, making them a critical focus for cancer research and treatment
… desmoplastic reaction, such as breast, colon, hepatobiliary, gastrointestinal, pancreatic, …

30 天前 - … of drug resistance that has been elucidated is the development of a unique desmoplastic
stroma that grows around the PDAC tumor … and creates a tumor microenvironment with …

37 天前 - … , due to a tumor microenvironment (TME) consisting of a desmoplastic stroma and
poor T cell … with mPDAC refractory to chemotherapy. Clinical trial information: NCT05558982. …

39 天前 - … diagnosis was much delayed and the patient started receiving chemotherapy, but
… Desmoplastic reaction adjacent to pancreatic cancer can be quite severe which can be …

43 天前 - … of pancreatic cancer that arises from the pancreatic ducts and accounts for more
than 90% of pancreatic cancer … (TME) comprising of desmoplastic stroma, cancer-associated …

51 天前 - … therapies such as chemotherapy, immunotherapy, and … of cell-based orthotopic
pancreatic cancer models in mice … collagen metabolism, tumor growth, and desmoplasia. It …

57 天前 - … Despite technological advancements, pancreatic cancer (PC) … desmoplasia and
hypovascular nature of the tumor, … cancer stages are managed with systemic chemotherapy. …

62 天前 - … stroma and desmoplastic reactions associated with pancreatic cancer cause
hypovascularity and a hypoxic microenvironment that evoke acquired chemoresistance by …

73 天前 - … chemoresistance resulting from the addiction of mutant-K-RAS/AKT/ERK
signaling-mediated desmoplastic … characteristics of human pancreatic cancer with desmoplasia …