Detection of β-lactamases in nosocomial gram negative clinical isolates

C Rodrigues, P Joshi, SH Jani, M Alphonse… - Indian journal of medical …, 2004 - Elsevier
Abstract β-lactamases represent the most common mechanism of β-lactam resistance.
Extended spectrum β-lactamases (ESBLs) represent a major group of β-lactamses currently
being identified worldwide in large numbers along with inducible AmpC β-lactamases and
derepressed mutants. The present study was done to detect β-lactamase production in
clinical isolates by rearranging routine discs used in reporting susceptibility to specifically
assess ESBLs, AmpC β-lactamases (both inducible and hyperproducers ie, derepressed …
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