In recent years, investigators have made great progress in delineating developmental
pathways of several lymphoid and myeloid lineages and in identifying transcription factors
that establish and maintain their fate. However, the developmental branching points
between these two large cell compartments are still controversial, and little is known about
how their diversification is induced. Here, we give an overview of determinants that play a
role at lymphoid-myeloid junctures, in particular transcription factors and cytokine receptors …