Polyacrylonitrile (PAN) can be used to bind together very small particles of absorbers into porous aggregates that can be used conveniently in packed columns. While binding the small particles together, the PAN allows substantial diffusion and even flow through the aggregates to give high effective mass transfer rates. Although PAN has been used or proposed for several applications, its capabilities for use with the US Department of Energy (DOE) radioactive wastes have not been determined. This paper summaries studies at the Czech Technical University on the stability of PAN-based absorbers under the radiation, chemical, and physical conditions needed for DOE wastes and assessments of their potential performance with selected US wastes.