Development of sensory neurons in the absence of NGF/TrkA signaling in vivo
TD Patel, A Jackman, FL Rice, J Kucera, WD Snider - Neuron, 2000 - cell.com
… To determine if the surviving sensory neurons innervate their peripheral targets in the
absence of NGF/TrkA signaling, we examined hindlimb skin and the mystacial pads of wild-type …
absence of NGF/TrkA signaling, we examined hindlimb skin and the mystacial pads of wild-type …
Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo
J Zhong, X Li, C McNamee, AP Chen, M Baccarini… - Nature …, 2007 - nature.com
… To explore the relationship between Raf signaling and the PEBP2 complex in vivo, we then
… We have previously shown in mice that lack NT3–TrkC signaling that that ventral projections …
… We have previously shown in mice that lack NT3–TrkC signaling that that ventral projections …
[HTML][HTML] Unraveling the story of NGF-mediated sensitization of nociceptive sensory neurons: ON or OFF the Trks?
GD Nicol, MR Vasko - Molecular interventions, 2007 - triggered.edina.clockss.org
… NGF-TrkA complex in turn activates a number of signaling … to that observed in cells grown
in the absence of NGF (54, 55). … Thus, in vivo studies attempting to elucidate NGF signaling in …
in the absence of NGF (54, 55). … Thus, in vivo studies attempting to elucidate NGF signaling in …
[PDF][PDF] Different signaling pathways mediate regenerative versus developmental sensory axon growth
RY Liu, WD Snider - The Journal of Neuroscience-The Official …, 2001 - Soc Neuroscience
… Nevertheless, in contrast to the situation with embryonic neurons, robust axon extension
from adult sensory neurons can occur in vitro in the absence of MEK/ERK or PI3-K signaling. …
from adult sensory neurons can occur in vitro in the absence of MEK/ERK or PI3-K signaling. …
Sensing life: regulation of sensory neuron survival by neurotrophins
M Kirstein, I Farinas - Cellular and Molecular Life Sciences CMLS, 2002 - Springer
… during development, both in vitro and in vivo. The number of … Physiologically, animals
deprived of NGF/trkA signaling … in vivo reported effects of the lack of NT-3 on sensory neuron pre…
deprived of NGF/trkA signaling … in vivo reported effects of the lack of NT-3 on sensory neuron pre…
NGF receptor expression in sensory neurons develops normally in embryos lacking NGF
AM Davies, S Wyatt, M Nishimura, H Phillips - Developmental biology, 1995 - Elsevier
… other cell lines suggest it is dispensable for NGF signaling. In … expression in developing
sensory neurons in vivo is regu… absence of NGF affects the sensitivity of developing neurons …
sensory neurons in vivo is regu… absence of NGF affects the sensitivity of developing neurons …
Characterization of an NGF–P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons
BA Tsui-Pierchala, DD Ginty - Journal of Neuroscience, 1999 - Soc Neuroscience
… , we asked whether the NGF–TrkA complex that forms in distal … sympathetic neurons
observed both in vitro and in vivo. … -independent sympathetic neurons in the absence of NGF. A, …
observed both in vitro and in vivo. … -independent sympathetic neurons in the absence of NGF. A, …
Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons
SR Wickramasinghe, RS Alvania, N Ramanan… - Neuron, 2008 - cell.com
… Development of sensory neurons in the absence of NGF/TrkA signaling in vivo. … to a loss
of neurotrophin receptors or a reduction of NGF-TrkA signaling. Our earlier observations that …
of neurotrophin receptors or a reduction of NGF-TrkA signaling. Our earlier observations that …
mGluR5 tunes NGF/TrkA signaling to orient spiny stellate neuron dendrites toward thalamocortical axons during whisker-barrel map formation
… The absence of mGluR5 increased the proportion of CP-AMPARs at … accounts for the aberrant
dendritic growth. … IV spiny stellate neurons because our in vivo TrkA inhibition experiments …
dendritic growth. … IV spiny stellate neurons because our in vivo TrkA inhibition experiments …
A local source of FGF initiates development of the unmyelinated lineage of sensory neurons
… becomes sufficient in the absence of Fgfr1. Furthermore, the … in vitro analysis, these data
suggest that FGF signaling via … Consistently, in the absence of Fgfr1 signaling, we found an …
suggest that FGF signaling via … Consistently, in the absence of Fgfr1 signaling, we found an …