Development refractoriness of MLL-rearranged human B cell acute leukemias to reprogramming into pluripotency
A Muñoz-López, D Romero-Moya, C Prieto… - Stem cell reports, 2016 - cell.com
Induced pluripotent stem cells (iPSCs) are a powerful tool for disease modeling. They are
routinely generated from healthy donors and patients from multiple cell types at different
developmental stages. However, reprogramming leukemias is an extremely inefficient
process. Few studies generated iPSCs from primary chronic myeloid leukemias, but iPSC
generation from acute myeloid or lymphoid leukemias (ALL) has not been achieved. We
attempted to generate iPSCs from different subtypes of B-ALL to address the developmental …
routinely generated from healthy donors and patients from multiple cell types at different
developmental stages. However, reprogramming leukemias is an extremely inefficient
process. Few studies generated iPSCs from primary chronic myeloid leukemias, but iPSC
generation from acute myeloid or lymphoid leukemias (ALL) has not been achieved. We
attempted to generate iPSCs from different subtypes of B-ALL to address the developmental …
Developmental refractoriness of MLL-rearranged human B-cell acute leukemias to reprogramming into pluripotency
A Muñoz, D Romero Moya, C Prieto… - … , 2016, vol. 7, num. 4, p …, 2016 - diposit.ub.edu
Induced pluripotent stem cells (iPSCs) are a powerful tool for disease modeling. They are
routinely generated from healthy donors and patients from multiple cell types at different
developmental stages. However, reprogramming leukemias is an extremely inefficient
process. Few studies generated iPSCs from primary chronic myeloid leukemias, but iPSC
generation from acute myeloid or lymphoid leukemias (ALL) has not been achieved. We
attempted to generate iPSCs from different subtypes of B-ALL to address the developmental …
routinely generated from healthy donors and patients from multiple cell types at different
developmental stages. However, reprogramming leukemias is an extremely inefficient
process. Few studies generated iPSCs from primary chronic myeloid leukemias, but iPSC
generation from acute myeloid or lymphoid leukemias (ALL) has not been achieved. We
attempted to generate iPSCs from different subtypes of B-ALL to address the developmental …
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