Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations in a rat model

MK Tamang, A Ali, RN Pertile, X Cui… - Translational …, 2023 - nature.com
Developmental vitamin D (DVD)-deficiency is an epidemiologically established risk factor for
autism. Emerging studies also highlight the involvement of gut microbiome/gut physiology in
autism. The current study aims to examine the effect of DVD-deficiency on a broad range of
autism-relevant behavioural phenotypes and gut health. Vitamin D deficient rat dams
exhibited altered maternal care, DVD-deficient pups showed increased ultrasonic
vocalizations and as adolescents, social behaviour impairments and increased repetitive …

Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations in a rat model

DW Eyles, MK Tamang, A Ali, R Pertile, X Cui… - 2022 - researchsquare.com
Developmental vitamin D (DVD)-deficiency is an epidemiologically established risk factor for
autism. Emerging studies also highlight the involvement of gut microbiome/gut physiology in
autism. The current study aims to examine the effect of DVD-deficiency on a broad range of
autism-relevant behavioural phenotypes and gut health. Vitamin D deficient rat dams
exhibited altered maternal care, DVD-deficient pups showed increased ultrasonic
vocalizations and as adolescents, social behaviour impairments and increased repetitive …
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