Diagnosis of acute tonsillopharyngitis in primary care: a new approach for low-resource settings

Z Alper, Y Uncu, H Akalin, I Ercan… - Journal of …, 2013 - Taylor & Francis
Journal of Chemotherapy, 2013Taylor & Francis
Abstract Background: Diagnosing GABHS (Group A-beta Hemolytic Streptococcus)
tonsillopharyngitis by clinical scoring is a recommended approach in developed countries,
but there is still much controversy for low resource settings. Aim: We aimed to assess the
impact of Centor criteria with the support of practical laboratory tests. Methods: We
prospectively included patients complaining sore throat (N= 282). We evaluated them in
terms of Centor scoring and performed white blood cell count (WBC), C-reactive protein …
Abstract
Background: Diagnosing GABHS (Group A-beta Hemolytic Streptococcus) tonsillopharyngitis by clinical scoring is a recommended approach in developed countries, but there is still much controversy for low resource settings.
Aim: We aimed to assess the impact of Centor criteria with the support of practical laboratory tests.
Methods: We prospectively included patients complaining sore throat (N = 282). We evaluated them in terms of Centor scoring and performed white blood cell count (WBC), C-reactive protein (CRP), rapid antigen detecting test, and throat culture.
Results: In GABHS cases (n = 32, 11·3%), two of the criteria were observed to be positive in more than half of the cases (n = 19, 59·3%), while 13 (40·7%) cases met three/four criteria. The specificity of having two criteria was found to be 65·5% and increased to 91·5% after including CRP and WBC.
Conclusion: Centor criteria could be safely used to reduce unnecessary antibiotic usage for tonsillopharyngitis in developing countries.
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