Diagnostic role of CD44 and desmoglein 3 in sinonasal inverted papilloma and associated squamous cell carcinoma
SA Hakim, W Ismail - Egyptian Journal of Pathology, 2016 - journals.lww.com
Background Sinonasal inverted papilloma (IP), although benign, is capable of local
invasiveness, recurrence, and malignant transformation and is especially related to
squamous cell carcinoma (SCC). Thus, additional markers for the detection of malignant
transformation tendencies of IP can help in reaching a correct diagnosis for proper
management. Aim The aim of this study was to evaluate the immunohistochemical
expression of CD44 and desmoglein 3 (DSG3) in normal sinonasal mucosa, sinonasal IP …
invasiveness, recurrence, and malignant transformation and is especially related to
squamous cell carcinoma (SCC). Thus, additional markers for the detection of malignant
transformation tendencies of IP can help in reaching a correct diagnosis for proper
management. Aim The aim of this study was to evaluate the immunohistochemical
expression of CD44 and desmoglein 3 (DSG3) in normal sinonasal mucosa, sinonasal IP …
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