Differences in airway remodeling between subjects with severe and moderate asthma
C Pepe, S Foley, J Shannon, C Lemiere… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: Airway remodeling in asthma comprises a range of structural changes.
Several studies have suggested an association between these changes and disease
severity. The relationship between the extent of remodeling and lung function is not well
defined. OBJECTIVE: We sought to contrast the structural changes in the airways of well-
defined groups of subjects with severe and moderate asthma and to correlate the extent of
remodeling with disease severity. METHODS: Endobronchial biopsy specimens were …
Several studies have suggested an association between these changes and disease
severity. The relationship between the extent of remodeling and lung function is not well
defined. OBJECTIVE: We sought to contrast the structural changes in the airways of well-
defined groups of subjects with severe and moderate asthma and to correlate the extent of
remodeling with disease severity. METHODS: Endobronchial biopsy specimens were …
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