Differential impact of blood pressure–lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation …
CAFé Investigators… - Circulation, 2006 - Am Heart Assoc
Background—Different blood pressure (BP)–lowering drugs could have different effects on
central aortic pressures and thus cardiovascular outcome despite similar effects on brachial
BP. The Conduit Artery Function Evaluation (CAFE) study, a substudy of the Anglo-
Scandinavian Cardiac Outcomes Trial (ASCOT), examined the impact of 2 different BP
lowering-regimens (atenolol±thiazide-based versus amlodipine±perindopril-based therapy)
on derived central aortic pressures and hemodynamics. Methods and Results—The CAFE …
central aortic pressures and thus cardiovascular outcome despite similar effects on brachial
BP. The Conduit Artery Function Evaluation (CAFE) study, a substudy of the Anglo-
Scandinavian Cardiac Outcomes Trial (ASCOT), examined the impact of 2 different BP
lowering-regimens (atenolol±thiazide-based versus amlodipine±perindopril-based therapy)
on derived central aortic pressures and hemodynamics. Methods and Results—The CAFE …
[PDF][PDF] Differential impact of blood pressure–lowering drugs on central aortic pressure and clinical outcomes
SM Thom, K Cruickshank, A Stanton, D Collier… - Circulation, 2006 - academia.edu
Background—Different blood pressure (BP)–lowering drugs could have different effects on
central aortic pressures and thus cardiovascular outcome despite similar effects on brachial
BP. The Conduit Artery Function Evaluation (CAFE) study, a substudy of the Anglo-
Scandinavian Cardiac Outcomes Trial (ASCOT), examined the impact of 2 different BP
lowering-regimens (atenololthiazide-based versus amlodipineperindopril-based therapy) on
derived central aortic pressures and hemodynamics. Methods and Results—The CAFE …
central aortic pressures and thus cardiovascular outcome despite similar effects on brachial
BP. The Conduit Artery Function Evaluation (CAFE) study, a substudy of the Anglo-
Scandinavian Cardiac Outcomes Trial (ASCOT), examined the impact of 2 different BP
lowering-regimens (atenololthiazide-based versus amlodipineperindopril-based therapy) on
derived central aortic pressures and hemodynamics. Methods and Results—The CAFE …
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