Differential Tumor Biology Between Locoregional and Distant Metastasis in a TENIS Patient with Tyrosine Kinase Inhibitor–Resistant Recurrent Disease: Comparative …

SN Sonavane, S Basu - Journal of Nuclear Medicine Technology, 2022 - Soc Nuclear Med
We present the molecular PET/CT imaging profile of an interesting case of differentiated
thyroid carcinoma that later transformed into TENIS (thyroglobulin elevation and negative
iodine scintigraphy) with tyrosine kinase inhibitor–resistant recurrent, aggressive disease.
The patient was evaluated to assess somatostatin receptor 2 or PSMA expression to explore
whether there might be any effective targeted nuclear therapy. 18F-FDG, 68Ga-DOTATATE,
and 68Ga-PSMA-11 PET/CT scans were obtained, all of which revealed tracer avidity in …

Differential tumor biology between locoregional and distant metastasis in a patient with TENIS with TKI-resistant aggressive recurrent disease: a comparative …

SN Sonavane, S Basu - Journal of Nuclear Medicine Technology, 2021 - Soc Nuclear Med
The molecular PET-CT imaging profile of an interesting case of differentiated thyroid
carcinoma, later transformed into with thyroglobulin elevation and negative iodine
scintigraphy (TENIS) with tyrosine kinase inhibitor (TKI) resistant recurrent aggressive
disease, is presented. The patient was evaluated to assess SSTR-2 or PSMA expression to
explore the possibility of any effective targeted nuclear therapy. 18 F-FDG, 68 Ga-
DOTATATE and 68 Ga-PSMA-11 PET/CT was performed, which revealed tracer avidity in all …
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