过去一年中添加的文章,按日期排序

[HTML][HTML] Pulmonary hypertension and the potential of 'drug'repurposing: A case for African medicinal plants

S Jacobs, C Payne, S Shaboodien… - African Journal of …, 2024 - samajournals.co.za
8 天前 - repurposing has been … drug repurposing as a viable option for PH. We provide
an overview of PH and highlight pharmaceutical drugs with repurposing potential, based on …

Repurposing of Plant-based Antiviral Molecules for the Treatment of COVID-19

J Khazir, S Ahmed, RK Thakur… - Current Topics in …, 2024 - ingentaconnect.com
134 天前 - … Hence, exploring drug discovery through repurposing … Direct transmission may
happen through respiratory … are needed to validate potential plant-based therapeutic agents. …

Developing a SARS-CoV-2 main protease binding prediction random forest model for drug repurposing for COVID-19 treatment

J Liu, L Xu, W Guo, Z Li, MKH Khan… - Experimental …, 2023 - journals.sagepub.com
232 天前 - … with the severe acute respiratory syndrome coronavirus 2 (… COVID-19 treatment
drugs that target the main protease … has been recognized as a potent drug target. In particular, …

Systematic Estimation of Treatment Effect on Hospitalization Risk as a Drug Repurposing Screening Method

C Georgantas, J Banus, R Hullin… - PACIFIC SYMPOSIUM …, 2023 - World Scientific
236 天前 - finding DR candidates usually rely on prior biological and chemical information on
a specific drug or target … cardiovascular, metabolic, and respiratory diseases. We determined …

… Neural Network Model for Effective Activity Prediction of SARS-CoV-2 Main Protease Inhibitors: Application to Drug Repurposing as Potential COVID-19 Therapy

Y Wu, K Li, M Li, X Pu, Y Guo - Journal of Chemical Information …, 2023 - ACS Publications
242 天前 - respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 main protease
(Mpro) has been proved to be an attractive drug target … 2 Mpro as therapeutic agents for COVID-…

Integrating artificial intelligence with bioinformatics promotes public health

H Hong, W Slikker - Experimental Biology and Medicine, 2023 - journals.sagepub.com
256 天前 - drug development lifecycle. This review also explores the challenges faced by data
scientists and researchers in the field of drug discovery … severe acute respiratory syndrome …

Chemoresistance Mechanisms in Non-Small Cell Lung Cancer—Opportunities for Drug Repurposing

R Kaur, PK Suresh - Applied Biochemistry and Biotechnology, 2023 - Springer
299 天前 - … , provides alternatives to the discovery of new, efficacious, and safe drugs. Therefore,
in … therapy-based chemoresistance mechanisms with the repurposed anti-cancer drugs