… 12–15, 20–22 The effects of dofetilide on action … 23 Dofetilide had similar effects on action
potential duration in normal and hypertrophied rabbit hearts, 24 and the effect of dofetilide was …

Dofetilide is a relatively new class III antiarrhythmic agent … Oral dofetilide is effective in the
conversion of atrial fibrillation … Unlike other antiarrhythmic agents, oral dofetilide did not …

… ) Study to evaluate whether dofetilide affects survival or morbidity … dofetilide was primarily
effective in patients with atrial fibrillation, 18,24 and this paper focuses on the use of dofetilide …

Dofetilide is a new antiarrhythmic agent recently approved for … Dofetilide prolongs the
effective refractory period in … In clinical trials dofetilide was superior to flecainide in converting …

… Articles were selected based on quality of review of the pharmacology and clinical use of
dofetilide. Given the paucity of data on the clinical pharmacology and use of dofetilide, most …

… , treatment with dofetilide did not affect all-cause mortality, cardiac mortality, or total
arrhythmic deaths. Dofetilide was effective in treating atrial fibrillation or flutter in this population. …

… dofetilide’s role in clinical practice. Due to its very specific mode of action, dofetilide has
very few systemic side-effects. Dofetilide represents a novel and promising new class III agent. …

… dofetilide … dofetilide and was used to engineer CHMs with HERG. We analyzed HERG/BEAG
CHMs to determine which protein domain is responsible for high-affinity block by dofetilide. …

… The present study investigated the potential of dofetilide in AF-AFl patients with left
ventricular dysfunction to restore and maintain sinus rhythm, which might reduce mortality and …

… Conclusions Dofetilide’s electrophysiologic and clinical … dofetilide, a pure class III agent
for the treatment of AF and atrial flutter (AFL). In this article, we review the features of dofetilide, …