2 天前 - … One of the most promising methods to enhance the solubility of therapeutic drugs is
the … , emphasizing the importance of optimizing both parameters to enhance drug solubility. …

4 天前 - Background Traditional Chinese medicine formulations often contain hydrophobic
components with limited solubility and stability, leading to low oral bioavailability. Self-…

9 天前 - … , we evaluated drug solubility in different release media and developed a method
for LOR … Furthermore, we identified the importance of considering the interplay between the …

9 天前 - … The most important feature in this work is the selectivity improvement for Ag + over
all interfering ions; the selectivity coefficient logarithm \({logK}_{Ag+, cation}^{opt}\) is found …

11 天前 - … One important advantage of sugar esters is the capacity of improving the solubility
of otherwise hydrophobic drugs, thus making formulation easier and taste improvement to …

11 天前 - … , whereas only 8% of drug candidates have high solubility and high permeability .
… improvement techniques of solubility and bioavailability of poorly soluble drug and the drugs …

17 天前 - … significantly enhanced. Considering the complexity of tumors and that a single
method … CD8 + T cells, we combined different drugs and the vaccine with Flt3L based on the …

17 天前 - … drug concentration above its equilibrium solubility in … methods, temperature-mediated
supersaturation is a highly considered and feasible approach to elevate the drug solubility …

17 天前 - … extensively applied in current years to overcome inadequate drug solubility concerns.
(1) … A review on solubility enhancement methods for poorly water-soluble drugs. J Rep …

27 天前 - … The integration of advanced computational techniques such as DFT, CFD, and
DEM has significantly improved our understanding of complex pharmaceutical processes. …