Dynamics of indel profiles induced by various CRISPR/Cas9 delivery methods
M Kosicki, SS Rajan, FC Lorenzetti, HH Wandall… - Progress in molecular …, 2017 - Elsevier
The introduction of CRISPR/Cas9 gene editing in mammalian cells is a scientific
breakthrough, which has greatly affected basic research and gene therapy. The simplicity
and general access to CRISPR/Cas9 reagents has in an unprecedented manner
“democratized” gene targeting in biomedical research, enabling genetic engineering of any
gene in any cell, tissue, organ, and organism. The ability for fast, precise, and efficient
profiling of the double-stranded break induced insertions and deletions (indels), mediated …
breakthrough, which has greatly affected basic research and gene therapy. The simplicity
and general access to CRISPR/Cas9 reagents has in an unprecedented manner
“democratized” gene targeting in biomedical research, enabling genetic engineering of any
gene in any cell, tissue, organ, and organism. The ability for fast, precise, and efficient
profiling of the double-stranded break induced insertions and deletions (indels), mediated …
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