Androgen-dependent oncogenic activation of ETS transcription factors by recurrent gene fusions in prostate cancer: biological and clinical implications

A Dobi, T Sreenath, S Srivastava - … -Responsive Genes in Prostate Cancer …, 2013 - Springer
ETS family of transcription factors have been in the focus of extensive research, the role of
ETS family of transcription factors in prostate … of prostate cancer-linked ETS transcription factors…

Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer

M Winnes, E Lissbrant, JE Damber… - Oncology …, 2007 - spandidos-publications.com
… clinical significance of ETS gene fusions in prostate cancer we have screened a series of 50
… I: Confirmation of the high frequency of the TMPRSS2/ERG fusion gene in prostate cancer. …

ETS transcription factors and prostate cancer: the role of the family prototype ETS-1

D Adler, N Wernert - International journal of oncology, 2012 - spandidos-publications.com
… review, we focus on studies investigating the role of ETS-1 in prostate cancer. … ETS family
members in prostate cancer, we have recently reported the expres sion pattern of all 27 ETS

Prevalence of ETS gene fusion in prostate cancer and its correlation with patients' clinicopathologic index

J Dong, L Xiao, Z Sun, L Sheng… - Chinese Journal of …, 2014 - pesquisa.bvsalud.org
Objective To explore the prevalence of ETS gene fusion in prostate cancer and its correlation
with patient's clinicopathologic index. Methods Ninety-one samples from prostate needle …

Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-Independent Metastatic Prostate Cancer

R Mehra, SA Tomlins, J Yu, X Cao, L Wang, A Menon… - Cancer research, 2008 - AACR
gene fusions may occur in some cases; however, many androgen-independent metastatic
prostate cancers with TMPRSS2-ETS fusion … TMPRSS2/ERG fusion gene in prostate cancer. …

TMPRSS2: ETS fusions and clinicopathologic characteristics of prostate cancer patients from Eastern China

J Dong, L Xiao, L Sheng, J Xu… - … Pacific Journal of Cancer …, 2014 - koreascience.kr
… Chinese prostate cancer patients have a significant lower incidence of TMPRSS2:ETS fusion
… Confirmation of the high frequency of the TMPRSS2/ERG fusion gene in prostate cancer. …

Androgen regulation of ETS gene fusion transcripts in prostate cancer

D Gasi, J Trapman - Androgen Action: Methods and Protocols, 2011 - Springer
… effects of ETS gene fusion in prostate cancer development … in commonly used LNCaP prostate
cancer cells grown with and … described for the identification of novel ETS fusion partners. …

ETS transcription factors: oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer

DP Turner, DK Watson - Expert review of anticancer therapy, 2008 - Taylor & Francis
… Specific examples of altered ETS factor expression are highlighted, and therapeutic … ETS
factors and their cofactors and downstream target genes in prostate cancer are discussed. …

Dissecting prostate carcinogenesis through ETS gene rearrangement studies: implications for anticancer drug development

G Attard, JE Ang, D Olmos, JS de Bono - Journal of clinical pathology, 2008 - jcp.bmj.com
… absence of formation of a fusion gene.5 Similarly, … ETS genes are common in prostate
cancer, and in the majority of cases appear to result in overexpression of the rearranged ETS gene

[HTML][HTML] Overview of research on fusion genes in prostate cancer

C Song, H Chen - Translational Cancer Research, 2020 - ncbi.nlm.nih.gov
fusion genes since the first specific fusion TMPRSS2-ERG was discovered in prostate cancer
… , FLI1 was the fifth ETS transcription factor involved in the PCa fusion genes (54) (Table 1). …