Effect of aclidinium bromide on major cardiovascular events and exacerbations in high-risk patients with chronic obstructive pulmonary disease: the ASCENT-COPD …
Importance There is concern that long-acting muscarinic antagonists increase
cardiovascular morbidity or mortality in patients with chronic obstructive pulmonary disease
(COPD). Objective To determine the cardiovascular safety (noninferiority) and efficacy
(superiority) of aclidinium bromide, 400 μg twice daily, in patients with COPD and
cardiovascular disease or risk factors. Design, Setting, and Participants Multicenter,
randomized, placebo-controlled, double-blind, parallel-design study conducted at 522 sites …
cardiovascular morbidity or mortality in patients with chronic obstructive pulmonary disease
(COPD). Objective To determine the cardiovascular safety (noninferiority) and efficacy
(superiority) of aclidinium bromide, 400 μg twice daily, in patients with COPD and
cardiovascular disease or risk factors. Design, Setting, and Participants Multicenter,
randomized, placebo-controlled, double-blind, parallel-design study conducted at 522 sites …
以上显示的是最相近的搜索结果。 查看全部搜索结果