Purpose Tegoprazan is a potassium-competitive acid blocker (P-CAB) that is designed to
treat acid-related diseases through a fundamentally different mechanism than that of proton
pump inhibitors (PPIs). Because PPIs inhibit only activated parietal cell H+/K+ adenosine
triphosphatase, stimulation of parietal cells by a meal is necessary for optimal results. In
contrast, P-CABs can inactivate proton pumps without acid activation and bind to both
activated and inactivated adenosine triphosphatase. This study evaluates the effect of food …