Effect of intensive lipid-lowering therapies on cholinesterase activity in patients with coronary artery disease

E Pytel, B Bukowska, M Koter-Michalak… - Pharmacological …, 2017 - Elsevier
Background Many disease entities, including coronary artery disease (CAD), demonstrate
abnormalities in the activity of cholinesterases. As CAD is characterized by an increase in
cholesterol level, patients with this disease are treated with lipid-lowering drugs. The present
study attempts to determine how statin or combined statin and ezetimibe therapy influences
cholinesterase activity. Methods Plasma and erythrocytes were isolated from the peripheral
blood of CAD patients (n= 61) and healthy subjects (n= 63). The patients were randomized …
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