… P (SP) and related neuropeptides to regulate the production of inflammatory cytokines by
human blood monocytes.We showed that the neuropeptides SP and substance K (SK) are …

… action of somatostatin on TNF-c~ and IL-113. In fact, the addition of these two inflammatory
cytokines to the monocyte … presence of the neuropeptide. Although somatostatin affected IL-8 …

… Human monocytes treated with various stimuli such as IL-1 or bacterial LPS … produce
abundant pro-inflammatory cytokines, an effect enhanced in genetically IL-37 deficient monocytes […

… Therefore, the amounts of cytokines produced by monocytes would … neuropeptides, with
demonstrated effects on the immune system, affect the production of pro-inflammatory cytokines…

… is regulated by a network of interacting cytokines and neuropeptides. Accordingly, pro-opiomelanocortin…
and anti-inflammatory mediators, mainly through regulating cytokine production. …

… neuropeptides and inflammatory cytokines have not been fully elucidated. We investigated
… effects of stimulation by CGRP and SP on the production of IL-1b, IL-6, and TNF-a in human …

… 1) production by human monocytes. This was confirmed in our experiments with human
monocytes … In addition, a wide variability of cell response to the neuropeptide was noticed. Three …

… , the expression levels in nonactivated monocytes of the proinflammatory cytokines TNF-α,
IL-… neuropeptide in the immune response and establish its modulating effects on monocytes. …

… from mouse bone-marrow precursors and human monocytes leads to the generation of DCs
… co-stimulatory molecules, low production of pro-inflammatory cytokines and increased IL-10 …

… antagonizes the effects of proinflammatory cytokines such as IL… aMSH also downregulates
the production of IFNy in human … MC-I on human monocytes. J Immunol 1997;158:3378-3384. …