Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial
Background Disturbance in the equilibrium of the gut microbiota has been involved in the
pathophysiology of depression. Probiotics have the potential to healthfully modulate the gut
microbiome. Prebiotics could also be effective by stimulation of growth of some bacterial
species in the gut microbiota. Objective The aim of this double blind clinical trial, was to
compare the effect of supplementation with the probiotic and prebiotic on the Beck
Depression Inventory (BDI) score as a primary outcome as well as the …
pathophysiology of depression. Probiotics have the potential to healthfully modulate the gut
microbiome. Prebiotics could also be effective by stimulation of growth of some bacterial
species in the gut microbiota. Objective The aim of this double blind clinical trial, was to
compare the effect of supplementation with the probiotic and prebiotic on the Beck
Depression Inventory (BDI) score as a primary outcome as well as the …
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