[PDF][PDF] Effects of empagliflozin on fluid overload, weight and blood pressure in chronic kidney disease
BACKGROUND: Chronic kidney disease (CKD) is associated with fluid excess which can be
estimated by bioimpedance spectroscopy. We aimed to assess effects of sodium glucose co-
transporter 2 inhibition on bioimpedance-derived “Fluid Overload” and adiposity in a CKD
population. METHODS: EMPA-KIDNEY was a double-blind placebo-controlled trial of
empagliflozin 10 mg once daily in patients with CKD at risk of progression. In a substudy,
bioimpedance measurements were added to the main trial procedures at randomization and …
estimated by bioimpedance spectroscopy. We aimed to assess effects of sodium glucose co-
transporter 2 inhibition on bioimpedance-derived “Fluid Overload” and adiposity in a CKD
population. METHODS: EMPA-KIDNEY was a double-blind placebo-controlled trial of
empagliflozin 10 mg once daily in patients with CKD at risk of progression. In a substudy,
bioimpedance measurements were added to the main trial procedures at randomization and …
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