This randomized, double-blind, placebo-controlled trial examined whether the
administration of ganglioside, an active ingredient of deer bone extract, can improve working
memory performance by increasing gray matter volume and functional connectivity in the
default mode network (DMN) in individuals with subjective cognitive impairment. Seventy-
five individuals with subjective cognitive impairment were chosen to receive either
ganglioside (330 μ g/day or 660 μ g/day) or a placebo for 8 weeks. Changes in working …

This randomized, double-blind, placebo-controlled trial examined whether the
administration of ganglioside, an active ingredient of deer bone extract, can improve working
memory performance by increasing gray matter volume and functional connectivity in the
default mode network (DMN) in individuals with subjective cognitive impairment. Seventy-
five individuals with subjective cognitive impairment were chosen to receive either
ganglioside (330 µg/day or 660 µg/day) or a placebo for 8 weeks. Changes in working …