Effects of spaceflight on murine skeletal muscle gene expression
DL Allen, ER Bandstra, BC Harrison… - Journal of Applied …, 2009 - journals.physiology.org
… First, to better understand the gene expression changes underlying the functional … to
spaceflight, we examined the effects of spaceflight on mRNA expression in gastrocnemius muscle …
spaceflight, we examined the effects of spaceflight on mRNA expression in gastrocnemius muscle …
[HTML][HTML] Gene Expression Profiling in Slow-Type Calf Soleus Muscle of 30 Days Space-Flown Mice
… the global gene expression changes induced by spaceflight. For example, changes in …
gene expression adaptation involved in microgravity-induced skeletal muscle atrophy in mouse …
gene expression adaptation involved in microgravity-induced skeletal muscle atrophy in mouse …
Skeletal muscle adaptations to microgravity exposure in the mouse
BC Harrison, DL Allen, B Girten… - Journal of applied …, 2003 - journals.physiology.org
… effects of microgravity exposure on skeletal muscle morphology and myosin heavy chain (MHC)
gene expression have … Spaceflight effects on single skeletal muscle fiber function in the …
gene expression have … Spaceflight effects on single skeletal muscle fiber function in the …
[HTML][HTML] Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent
… To assess circadian gene expression in WT mice and the impact of circadian clock alterations
in mouse skeletal muscle, we analysed time-course microarray datasets derived from WT …
in mouse skeletal muscle, we analysed time-course microarray datasets derived from WT …
Spaceflight effects on T lymphocyte distribution, function and gene expression
DS Gridley, JM Slater, X Luo-Owen… - Journal of applied …, 2009 - journals.physiology.org
… T cells in culture that were mitogen/antibody-activated and our mouse data on constitutive
gene expression are difficult because of the obviously great differences in study conditions. …
gene expression are difficult because of the obviously great differences in study conditions. …
[HTML][HTML] Effects of spaceflight on the muscles of the murine shoulder
… muscle gene expression after SF We compared changes in gene expression in 3 shoulder
muscles—… to microgravity as well as the complexity in regulation of skeletal muscle size and …
muscles—… to microgravity as well as the complexity in regulation of skeletal muscle size and …
[HTML][HTML] Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space
… between spaceflight … skeletal muscles lose mass in space, we performed RNAseq analysis
on the soleus and gastrocnemius to ascertain differences in gene expression profiles in mice …
on the soleus and gastrocnemius to ascertain differences in gene expression profiles in mice …
Spaceflight reduces vasoconstrictor responsiveness of skeletal muscle resistance arteries in mice
JN Stabley, JM Dominguez… - Journal of Applied …, 2012 - journals.physiology.org
… mRNA expression. Vessel wall thickness and maximal intraluminal diameter were unaffected
by spaceflight… -3 in smooth muscle cells as the mechanism of reduced contractile activity in …
by spaceflight… -3 in smooth muscle cells as the mechanism of reduced contractile activity in …
Factors mediating spaceflight-induced skeletal muscle atrophy
… ), and IL-10 mRNA expression in skeletal muscle after 7-day bed … hindlimb immobilization
in mice lead to skeletal muscle atrophy … of mitochondrion-associated gene expression (157). …
in mice lead to skeletal muscle atrophy … of mitochondrion-associated gene expression (157). …
[HTML][HTML] Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission
… after space flight (see gene expression below), consistent with the knowledge that skeletal
muscle … In addition, the number of muscle fiber nuclei was reported to decrease in adult rats …
muscle … In addition, the number of muscle fiber nuclei was reported to decrease in adult rats …