Background Recent studies have shown that novel neuro-modulating techniques can have
pain-relieving effects in the treatment of chronic pain. The aim of this work is to evaluate the
effects of transcranial direct current stimulation (tDCS) in relieving fibromyalgia pain and its
relation with beta-endorphin changes. Material and methods Forty eligible patients with
primary fibromyalgia were randomized to receive real anodal tDCS or sham tDCS of the left
motor cortex (M1) daily for 10 days. Each patient was evaluated using widespread pain …