[PDF][PDF] Elucidating Epigenetic Regulation by Identifying Functional cisActing Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage

M van Hoolwerff, PI Metselaar… - Arthritis & …, 2020 - Wiley Online Library
lncRNAs are prone to regulate mRNAs in cis in OA cartilage. … long noncoding RNAs (lncRNAs)
and previously identified … antisense differentially expressed lncRNAs and differentially …

Regulation of gene expression by cis-acting long non-coding RNAs

N Gil, I Ulitsky - Nature Reviews Genetics, 2020 - nature.com
Long non-coding RNAs (lncRNAs) are diverse transcription … pivotal step when beginning to
elucidate their roles. This step … , genomic neighbourhood, epigenetic environment and mode …

Epigenetic regulation by long noncoding RNAs

JT Lee - Science, 2012 - science.org
LncRNA’s function is not limited to the control of allelic expression (Table 1). In addition to the
RIP-seq analysis identifying thousands of RNAs in … would need elucidation before general …

Functional identification of cis-regulatory long noncoding RNAs at controlled false discovery rates

B Dhaka, M Zimmerli, D Hanhart, MB Moser… - Nucleic acids …, 2024 - academic.oup.com
… a quantitative foundation for cis-lncRNAs, opening a path to elucidating their molecular …
,CP (2014) The long non-coding RNA Dali is an epigenetic regulator of neural differentiation. …

The role of long noncoding RNAs in the epigenetic control of gene expression

M Morlando, M Ballarino, A Fatica, I Bozzoni - ChemMedChem, 2014 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a newly identified … these lncRNAs are involved in
epigenetic regulation, acting as … be elucidated about the structure and function of these lncRNAs, …

Emerging epigenetic mechanisms of long non-coding RNAs

K Schaukowitch, TK Kim - Neuroscience, 2014 - Elsevier
Long non-coding RNAs (lncRNAs) have been increasingly … begun to elucidate the functional
mechanisms of lncRNAs. In … of the cis regulatory mechanism by which lncRNAs expressed …

Long noncoding RNA modifies chromatin: epigenetic silencing by long noncoding RNAs

A Saxena, P Carninci - Bioessays, 2011 - Wiley Online Library
… mechanisms of long non-coding RNA-mediated gene repression. … The elucidation of the
molecular mechanisms of such long-… in epigenetic regulation by lncRNAs, it is important to first …

Cis-acting noncoding RNAs: friends and foes

S Guil, M Esteller - Nature structural & molecular biology, 2012 - nature.com
… and remodelers to change the epigenetic status of target genes 7,8,9,… class of enhancer-related
long noncoding RNAs (lncRNAs). … remains to be elucidated, the functional impact reveals …

Behind the scenes: How RNA orchestrates the epigenetic regulation of gene expression

A Mangiavacchi, G Morelli, V Orlando - Frontiers in Cell and …, 2023 - frontiersin.org
RNAs, particularly long non-coding RNA (lncRNA), enhancer … not prove the functional aspects
of in silico-identified enhancers. … to elucidate the role of sncRNAs as epigenetic regulators. …

Gene regulation by the act of long non-coding RNA transcription

AE Kornienko, PM Guenzl, DP Barlow, FM Pauler - BMC biology, 2013 - Springer
… (d) or in cis like HOTTIP (e) by directly recruiting epigenetic … point to determine lncRNA
function has been RNA interference (… may elucidate the function of lncRNAs acting through their …