Embryo aneuploidy screening for repeated implantation failure and unexplained recurrent miscarriage

N Findikli, S Kahraman, Y Saglam… - Reproductive …, 2006 - Elsevier
Among other factors, chromosomal abnormalities that originate from gametogenesis and
preimplantation embryonic development are thought to be one of the major contributing
factors for early embryonic death and failure of pregnancy. However, so far, no non-invasive
technique exists that allows the detection of the chromosomal complement of an oocyte or a
developing embryo as a whole. Rather, by removing polar bodies/blastomeres, recent
developments on preimplantation genetic diagnosis for aneuploidy screening (PGD-AS) …
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