7 天前 - … The androgen receptor (AR) is a drug target used to inhibit AR and prostate cancer
(… that the atypical tumor suppressive cyclin G2 emerged as a novel downstream target of …

8 天前 - … in metastatic hormone-sensitive prostate cancer (mHSPC), … of androgen deprivation
therapy and androgen receptor (AR)-… prostate cancer using WB-MRI are now emerging. …

9 天前 - … mechanisms are being overcome and targeted protein degradation is widening the
… the oestrogen receptor and androgen receptor in breast and prostate cancer respectively. …

29 天前 - … We also sought to identify molecular alterations of the androgen receptor (AR),
including fusions… Repurposing kinase inhibitors in combination with AR inhibitors might be a new …

30 天前 - … : Breast cancer (BC) is the most diagnosed cancer globally with over 2.2 million
new … cases are radio-resistant, with the underlying mechanisms remaining poorly understood…

53 天前 - Background: Treatment resistance in prostate cancer can be the result of multiple
different tumour cell adaptations generating castration-resistant prostate cancer (CRPC). …

58 天前 - … Androgen receptor (AR) is the primary target for treating prostate cancer (PCa), which
… Bromodomain-containing protein 4 (BRD4) has been a new potential drug target for PCa …

59 天前 - … of all three drugs under this condition (p < 0.0001 for all drugs). … tumors with low
androgen receptor activities and high … new efficacious therapeutics beyond traditional androgen-…

64 天前 - … androgen receptor pathway, the current evidence on PARP inhibitors activity in
metastatic prostate cancer … well as emerging mechanisms of resistance to PARP inhibitors. The …

71 天前 - … Prostate cancer (PCa) and breast cancer (BCa) are usually dependent on steroid …
receptors signaling, specifically the androgen receptor (AR) in PCa and the estrogen receptor …