… Here, we highlight the role of CTD modifications in directing transcription … of the CTD code
and examine the relevance of describing patterns of posttranslational modifications as a “code.…

… The emerging importance of CTD plasticity requires future dynamic studies, including
those at the single molecule level. By combining the structural and dynamic data of the …

… A role of the CTD in these processes is just emerging. Here … A CTD code could consist of 16
different states of the CTD repeat… when one considers how a CTD code may be read, in other …

… of the CTD are emerging with unanticipated roles in gene expression regulation. … This
review focuses on recent developments that are transforming our view of the CTD and …

… From bacteria to mammals, all cells use the same nucleic acid-based universal code for the
… II (RNAPII) and will be termed the CTD (C-terminal domain) throughout this Review. RNA …

… as a binary code, where the presence or absence of modification can influence factor–CTD …
elements that can contribute to a CTD code and explain how this code is ‘read’ by proteins …

… (10) In this article, we will review the literature on the CTD code, … Below, we will summarize
the current view of the CTD … Then, we will review the emerging function of the CTD in …

… CTD code and how the newly characterized physicochemical properties of the CTD expand
the function of the CTD beyond the code… , whereas for others the role of the CTD is emerging. …

… Complex with Phosphorylated Pol II CTD (A) A view of the Mce-CTD structure shown in
ribbon … The most instructive findings emerged from the combination of C383Y and R330A/K331A. …

… code, most amino acids can be specified by several codons. If we assume that the CTD …
evolved in a stepwise manner before a sequence of SPSYSPT heptads emerged that could …