Comparative study of Regulatory requirements of Drug Product in Emerging market

P Patel, JK Badjatya, M Hinge - International Journal of Drug …, 2019 - indianjournals.com
… document (CTD) filing, while there is diversity of requirements in emerging markets. … are
is no such harmonized guideline for emerging market except Association of Southeast Asian …

Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code

M Zhang, XJ Wang, X Chen, ME Bowman… - ACS chemical …, 2012 - ACS Publications
… Scp1 is the first structurally characterized CTD-specific phosphatase with its substrate bound
in humans. (21-23) In our high-resolution structure of the Scp1-CTD complex (PDB code: …

RNAPII CTD: A key regulator in eukaryotic gene expression system

M Kashif, A Ahmad, S Siddiqui, B Kumar, MJ Khan - Gene Reports, 2018 - Elsevier
CTD enables changes in the tethered activities as RNAPII proceeds through the transcription
cycle. This is the basis of the CTD code that has emerged … language of CTD modifications, …

The RNA polymerase II CTD “orphan” residues: Emerging insights into the functions of Tyr-1, Thr-4, and Ser-7

NM Yurko, JL Manley - Transcription, 2018 - Taylor & Francis
… More recent studies have complicated somewhat the view of Ser7 in snRNA gene expression.
… The idea that CTD codes might be different for different organisms also arose from studies …

Fission yeast RNA triphosphatase reads an Spt5 CTD code

SK Doamekpor, B Schwer, AM Sanchez, S Shuman… - Rna, 2015 - rnajournal.cshlp.org
… Our results fortify an emerging concept of an “Spt5 CTD code” in which (i) the Spt5 CTD is
… The surface view in Figure 1C highlights the proximity of the Spt5 CTD to the homodimer …

Structural basis of an essential interaction between influenza polymerase and Pol II CTD

M Lukarska, G Fournier, A Pflug, P Resa-Infante… - Nature, 2017 - nature.com
… c, View of the interaction between CTD and bat FluA in site 2, showing the position of the …
with the following accession codes: bat influenza A polymerase CTD peptide complex, 5M3H. …

Emerging roles for RNA polymerase II CTD in Arabidopsis

M Hajheidari, C Koncz, D Eick - Trends in plant science, 2013 - cell.com
… Compared with the progress in yeast and mammals, deciphering the regulatory roles of
position-specific combinatorial CTD modifications, the so-called CTD code, is still at an early …

Gene‐specific requirement of RNA polymerase II CTD phosphorylation

J Drogat, D Hermand - Molecular microbiology, 2012 - Wiley Online Library
… potential referred to as the CTD code. In order to gain insight into … Recently, this view was
further supported by the elegant … Until recently, all of the above conclusions and the emerging

Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation

GJ Morgan, FE Davies, WM Gregory… - Blood, The Journal …, 2011 - ashpublications.org
As part of the randomized MRC Myeloma IX trial, we compared an attenuated regimen of
cyclophosphamide, thalidomide, and dexamethasone (CTDa; n = 426) with melphalan and …

Forecast of drifter trajectories using a Rapid Environmental Assessment based on CTD observations

R Sorgente, C Tedesco, F Pessini… - Deep Sea Research …, 2016 - Elsevier
… During the exercise, CTD data have been collected … the impact of such mesoscale-resolving
CTD observations on short-term … The effect of the wind on the emerged part of the CODE is …