Comparative study of Regulatory requirements of Drug Product in Emerging market
P Patel, JK Badjatya, M Hinge - International Journal of Drug …, 2019 - indianjournals.com
… document (CTD) filing, while there is diversity of requirements in emerging markets. … are
is no such harmonized guideline for emerging market except Association of Southeast Asian …
is no such harmonized guideline for emerging market except Association of Southeast Asian …
Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code
M Zhang, XJ Wang, X Chen, ME Bowman… - ACS chemical …, 2012 - ACS Publications
… Scp1 is the first structurally characterized CTD-specific phosphatase with its substrate bound
in humans. (21-23) In our high-resolution structure of the Scp1-CTD complex (PDB code: …
in humans. (21-23) In our high-resolution structure of the Scp1-CTD complex (PDB code: …
RNAPII CTD: A key regulator in eukaryotic gene expression system
M Kashif, A Ahmad, S Siddiqui, B Kumar, MJ Khan - Gene Reports, 2018 - Elsevier
… CTD enables changes in the tethered activities as RNAPII proceeds through the transcription
cycle. This is the basis of the CTD code that has emerged … language of CTD modifications, …
cycle. This is the basis of the CTD code that has emerged … language of CTD modifications, …
The RNA polymerase II CTD “orphan” residues: Emerging insights into the functions of Tyr-1, Thr-4, and Ser-7
NM Yurko, JL Manley - Transcription, 2018 - Taylor & Francis
… More recent studies have complicated somewhat the view of Ser7 in snRNA gene expression.
… The idea that CTD codes might be different for different organisms also arose from studies …
… The idea that CTD codes might be different for different organisms also arose from studies …
Fission yeast RNA triphosphatase reads an Spt5 CTD code
SK Doamekpor, B Schwer, AM Sanchez, S Shuman… - Rna, 2015 - rnajournal.cshlp.org
… Our results fortify an emerging concept of an “Spt5 CTD code” in which (i) the Spt5 CTD is
… The surface view in Figure 1C highlights the proximity of the Spt5 CTD to the homodimer …
… The surface view in Figure 1C highlights the proximity of the Spt5 CTD to the homodimer …
Structural basis of an essential interaction between influenza polymerase and Pol II CTD
M Lukarska, G Fournier, A Pflug, P Resa-Infante… - Nature, 2017 - nature.com
… c, View of the interaction between CTD and bat FluA in site 2, showing the position of the …
with the following accession codes: bat influenza A polymerase CTD peptide complex, 5M3H. …
with the following accession codes: bat influenza A polymerase CTD peptide complex, 5M3H. …
Emerging roles for RNA polymerase II CTD in Arabidopsis
M Hajheidari, C Koncz, D Eick - Trends in plant science, 2013 - cell.com
… Compared with the progress in yeast and mammals, deciphering the regulatory roles of
position-specific combinatorial CTD modifications, the so-called CTD code, is still at an early …
position-specific combinatorial CTD modifications, the so-called CTD code, is still at an early …
Gene‐specific requirement of RNA polymerase II CTD phosphorylation
J Drogat, D Hermand - Molecular microbiology, 2012 - Wiley Online Library
… potential referred to as the CTD code. In order to gain insight into … Recently, this view was
further supported by the elegant … Until recently, all of the above conclusions and the emerging …
further supported by the elegant … Until recently, all of the above conclusions and the emerging …
Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation
GJ Morgan, FE Davies, WM Gregory… - Blood, The Journal …, 2011 - ashpublications.org
As part of the randomized MRC Myeloma IX trial, we compared an attenuated regimen of
cyclophosphamide, thalidomide, and dexamethasone (CTDa; n = 426) with melphalan and …
cyclophosphamide, thalidomide, and dexamethasone (CTDa; n = 426) with melphalan and …
Forecast of drifter trajectories using a Rapid Environmental Assessment based on CTD observations
R Sorgente, C Tedesco, F Pessini… - Deep Sea Research …, 2016 - Elsevier
… During the exercise, CTD data have been collected … the impact of such mesoscale-resolving
CTD observations on short-term … The effect of the wind on the emerged part of the CODE is …
CTD observations on short-term … The effect of the wind on the emerged part of the CODE is …