Emodin induces apoptosis and suppresses non-small-cell lung cancer growth via downregulation of sPLA2-IIa
Background Lung cancer has become the principal cause of cancer-related deaths. Emodin
is a Chinese herb-derived compound extracted from the roots of Rheum officinale that
exhibits numerous pharmacological characteristics. Secretory phospholipase A2-IIa (sPLA2-
IIa) is overexpressed in cancers and plays an important role in cancer development.
Purpose This study aims to investigate the anti-tumor mechanism of emodin in non-small-
cell lung cancer (NSCLC). Methods MTT assay was applied to detect the sensitivity of …
is a Chinese herb-derived compound extracted from the roots of Rheum officinale that
exhibits numerous pharmacological characteristics. Secretory phospholipase A2-IIa (sPLA2-
IIa) is overexpressed in cancers and plays an important role in cancer development.
Purpose This study aims to investigate the anti-tumor mechanism of emodin in non-small-
cell lung cancer (NSCLC). Methods MTT assay was applied to detect the sensitivity of …
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