Objective Energy loss is a biomechanical parameter that represents the relative amount of
energy absorbed by the aorta during the cardiac cycle. We aimed to correlate energy loss
with ascending aortic aneurysm size and histopathologic findings to elucidate the
pathophysiology of aneurysm complications. Methods Aneurysmal ascending aortic
specimens were obtained during surgery. Control specimens were obtained from autopsy
and organ donors. Biaxial tensile tests were performed on the 4 quadrants of the aortic ring …

It is not well understood which ascending aortas will develop complications. Biomechanics
may provide insights beyond the consideration of size alone, and improve risk prediction.
Energy loss is a biomechanical parameter describing the relative amount of energy
absorbed by the aorta during the cardiac cycle. We aim to correlate energy loss with
ascending aortic aneurysm size and histopathology to elucidate the pathophysiology of
aneurysm complications.