过去一年中添加的文章,按日期排序

Quinone Methide Precursors for the Recovery of Native Enzyme Activity from Organophosphorus-Intoxicated Acetylcholinesterase and Butyrylcholinesterase

WK Clay - 2024 - rave.ohiolink.edu
2 天前 - Organophosphorus (OP) compounds are highly toxic to the human body via the
inhibition of the essential enzyme acetylcholinesterase (AChE). After phosphylation of the …

Chemoenzymatic Synthesis of Fluorinated L-α-Amino Acids

X Jin, C Huang, C Cui, H Liu, Z Liu… - ACS Sustainable …, 2024 - ACS Publications
24 天前 - … , the conventional chemical synthesis of fluorinated amino … recycling process in
enzymatic synthesis have limited … for the asymmetric synthesis of chiral fluorinated amino acids. …

Asymmetric photoenzymatic incorporation of fluorinated motifs into olefins

M Li, Y Yuan, W Harrison, Z Zhang, H Zhao - Science, 2024 - science.org
57 天前 - … This work advances enzymatic strategies for integrating fluorinated chemical
feedstocks and opens avenues for asymmetric synthesis of fluorinated compounds. Fluorine’s …

[PDF][PDF] Zh., Fazylov SD, Seilkhanov TM, Kabieva SK, Satbayeva EM, Karipova G. Zh., Syzdykov AK Synthesis of quaternary ammonium salts isonicotinic and nicotinic …

OA Nurkenov, A Mendibayeva - … CHEMICAL JOURNAL of …, 2024 - researchgate.net
131 天前 - fluorine and bromine-containing fragments into their structure. The structure of …
compounds may have an effect on the regulation and production of ketone bodies, the enzymatic

Biocatalytic enantioselective C(sp3)–H fluorination enabled by directed evolution of non-haem iron enzymes

LP Zhao, BK Mai, L Cheng, F Gao, Y Zhao, R Guo… - … Synthesis, 2024 - nature.com
148 天前 - … Despite these notable advances, new-to-nature enzymatic C–F bond formation …
fluorination enzymatic functions is in stark contrast to the ubiquity of organofluorine compounds

Enzymatic Stereodivergent Access to Fluorinated β-Lactam Pharmacophores via Triple-Parameter Engineered Ketoreductases

ZL Mei, CC Li, X Han, YC Tian, SH Li, W Liu, G Qu… - ACS …, 2024 - ACS Publications
163 天前 - … We accomplished the synthesis of fluoroalkyl β-hydroxyl-β′-amino acid esters via
enzymatic reductive dynamic kinetic transformation of β-ketoesters. By taking advantage of …

CИНТЕЗ ЧЕТВЕРТИЧНЫХ АММОНИЕВЫХ СОЛЕЙ ГИДРАЗОНОВ ИЗОНИКОТИНОВОЙ И НИКОТИНОВОЙ КИСЛОТ И ИХ ПРОТИВОВОСПАЛИТЕЛЬНАЯ …

S Fazylov, O Nurkenov, A Mendibayeva… - Chemical Journal of …, 2024 - chemjournal.kz
174 天前 - fluorine and bromine-containing fragments into their structure. The structure of …
compounds may have an effect on the regulation and production of ketone bodies, the enzymatic

Advances in Enzymatic Incorporation of Small Fluorine Modules

Y Lin, W Xue, H Li, B Su, J Lin… - European Journal of …, 2024 - Wiley Online Library
176 天前 - … In this review, we present the discovery of fluorinated … in the enzymatic synthesis
of fluorine-containing compounds in … field of biocatalytic organofluorine compound synthesis. …

Engineering non-haem iron enzymes for enantioselective C(sp3)–F bond formation via radical fluorine transfer

Q Zhao, Z Chen, J Soler, X Chen, J Rui, NT Ji, QE Yu… - … Synthesis, 2024 - nature.com
177 天前 - … Nevertheless, our findings represent the first redox process for enzymatic C–F
bond formation and a rare example of highly enantioselective radical C(sp 3 )–H …

Supercharging green chemistry: Unleashing 1, 4‐NADH regeneration and unprecedented C(sp3)‐F bond activation via NiS‐NiO/S‐g‐C3N4 nanocomposite …

S Kumari, AP Singh, RK Yadav, S Singh… - Asia‐Pacific Journal …, 2024 - Wiley Online Library
276 天前 - … The need for selective 1,4-NADH cofactor regeneration and fluorination has increased
due to the widespread use of enzymatically active NADH and fluorinated compounds as …