过去一年中添加的文章,按日期排序

Current advances in targeted therapy for metastatic colorectal cancer–Clinical translation and future directions

D Johnson, CE Chee, W Wong, RCT Lam… - Cancer Treatment …, 2024 - Elsevier
94 天前 - … left-sided primary tumor for treatment with epidermal growth factor receptor (EGFR)
and … therapies using Next Generation Sequencing analysis of circulating tumor-derived DNA …

[HTML][HTML] Harnessing Luteolin's Therapeutic Potential in Human Disorders: Medicinal Significance, Biological, Clinical Properties and Analytical aspects

A Singh, S Yadav, P Pathak, A Verma… - … Modern Chinese Medicine, 2024 - Elsevier
96 天前 - … protein 2; EGFR, Epidermal growth factor receptor; FZD6, Frizzled class receptor6;
FZJDXJ, Fuzheng Jiedu Xiaoji formulation; GBM, Glioblastoma multiforme grade IV; H. pylori, …

Rational design and synthesis of 2,4‐dichloro‐6‐methyl pyrimidine derivatives as potential selective EGFRT790M/L858R inhibitors for the treatment of non‐small cell …

L Duan, C Chu, X Huang, H Yao, J Wen… - Archiv der …, 2024 - Wiley Online Library
97 天前 - epidermal growth factor receptor (EGFR) targeted therapy. … detailed the marketed
EGFR inhibitors, analyzed their … resistance pathways of EGFR‐targeted therapy for NSCLC. …

[PDF][PDF] Diallyl trisulfide inhibits osteosarcoma 143B cell migration, invasion and EMT by inducing autophagy

X Liu, N Wang, Z He, C Chen, J Ma, X Liu, S Deng… - Heliyon, 2024 - cell.com
97 天前 - … expression of epidermal growth factor receptor (EGFR) in … Moreover, EGFR inhibitors
have exhibited significant anti-… that EGFR is an important target of DATS in the treatment

[HTML][HTML] Erlotinib combination with a mitochondria-targeted ubiquinone effectively suppresses pancreatic cancer cell survival

PY Leung, W Chen, AN Sari, P Sitaram… - World Journal of …, 2024 - wjgnet.com
97 天前 - … ) is often observed in pancreatic cancer, and the small molecule EGFR inhibitor
therapy Core Tip: In this study, we demonstrated that epidermal growth factor receptor inhibitor

[HTML][HTML] Resistance of HNSCC cell models to pan-FGFR inhibition depends on the EMT phenotype associating with clinical outcome

F Broghammer, I Korovina, M Gouda, M Celotti… - Molecular Cancer, 2024 - Springer
98 天前 - … Such therapies require a detailed understanding of … when the epidermal growth
factor receptor (EGFR) is inhibited … In summary, the in vitro derived transcriptomic FGFRi-…

Metabolic characterization of colorectal cancer cells upon acquired resistance to anti-EGFR therapy

R Al Roumi, C Corbet - dial.uclouvain.be
99 天前 - … with anti-EGFR (epidermal growth factor receptor) targeted therapies (cetuximab),
the … to recycle glycolysis-derived lactate to sustain their growth. This was associated with an …

ELK1/MTOR/S6K1 Pathway Contributes to Acquired Resistance to Gefitinib in Non-Small Cell Lung Cancer

L Zhao, Y Wang, X Sun, X Zhang, N Simone… - International Journal of …, 2024 - mdpi.com
101 天前 - therapy options, small molecule tyrosine kinase inhibitors (TKIs) targeting epidermal
growth factor receptor (EGFR… gefitinib in an NSCLC patient-derived xenograft (PDX) model …

EfficientNet-Based System for Detecting EGFR-Mutant Status and Predicting Prognosis of Tyrosine Kinase Inhibitors in Patients with NSCLC

N Xu, J Wang, G Dai, T Lu, S Li, K Deng… - … Informatics in Medicine, 2024 - Springer
103 天前 - epidermal growth factor receptor (EGFR) in patients with NSCLC and developing
targeted therapies with EGFR tyrosine kinase inhibitors … likely to derive benefits from EGFR-TKI…

[PDF][PDF] Taraxasterol stimulates apoptosis of BCa cells via restraining PI3K/AKT and epidermal growth factor receptor (EGFR)

Y Hu, X Zhang, S Zhao - Eur. J. Gynaecol. Oncol, 2024 - oss.ejgo.net
103 天前 - … To combat BCa, EGFR inhibitors such as gefitinib, … BCa cell proliferation and
improving treatment outcomes [5]. … can be obtained from the corresponding author upon request. …