过去一年中添加的文章，按日期排序
[HTML][HTML] A phase I study of Hemay022, an irreversible dual EGFR/HER2 tyrosine kinase inhibitor in Chinese patients with HER2-positive advanced breast cancer
P Zhang, L Wang, Y Zhen, Z Wang… - Chinese Journal of …, 2024 - ncbi.nlm.nih.gov
116 天前 - … receptor (EGFR)/human epidermal growth factor receptor … Pharmacokinetic samples
were obtained on d 1 and d 28. … therapy of pyrotinib (an irreversible EGFR/HER2 inhibitor). …
were obtained on d 1 and d 28. … therapy of pyrotinib (an irreversible EGFR/HER2 inhibitor). …
[HTML][HTML] 46P Dynamics of ROS1 kinase binding: Insights into DFG-out tyrosine kinase inhibitors and effects of allosteric-pocket mutations
FU Haq, KO de Beeck, G Van Camp, G Vandeweyer - ESMO Open, 2024 - esmoopen.com
117 天前 - … -cancer therapies using tyrosine kinase inhibitors (TKIs) have achieved success
in the past for related kinase targets, including epidermal growth factor receptor (EGFR) and …
in the past for related kinase targets, including epidermal growth factor receptor (EGFR) and …
[HTML][HTML] A New Benzo [6, 7] oxepino [3, 2-b] Pyridine Derivative Induces Apoptosis in Canine Mammary Cancer Cell Lines
N Jianpraphat, W Supsavhad, P Ngernmeesri… - Animals, 2024 - mdpi.com
124 天前 - … -2, BAX, epidermal growth factor receptor (EGFR), snail … palliative therapy following
the surgical treatment of CMC … cells could inhibit the epidermal growth factor that induces …
the surgical treatment of CMC … cells could inhibit the epidermal growth factor that induces …
[PDF][PDF] Results in Chemistry
IM Al-Rubaye, AAR Mahmood, LH Tahtamouni… - researchgate.net
125 天前 - … of the epidermal growth factor receptor (EGFR) causes an … As an anticancer therapy,
targeting the EGFR allosteric … the development of resistance to EGFR inhibitors. As a result, …
targeting the EGFR allosteric … the development of resistance to EGFR inhibitors. As a result, …
Tissue-resident macrophages exacerbate lung injury after remote sterile damage
H Zhong, J Ji, J Zhuang, Z Xiong, P Xie, X Liu… - Cellular & molecular …, 2024 - nature.com
132 天前 - … for treating secondary complications of sterile damage. … RAGE- and epidermal
growth factor receptor (EGFR)-driven … whether monocyte-derived macrophages contributed to …
growth factor receptor (EGFR)-driven … whether monocyte-derived macrophages contributed to …
[HTML][HTML] Therapeutic potential of Hyoscyamus niger-derived compounds: Targeting ovarian cancer through antioxidant activity and EGFR tyrosine kinase inhibition
S Lekmine, O Benslama, K Kadi… - Journal of King Saud …, 2024 - Elsevier
133 天前 - … epidermal growth factor-receptor (EGFR) tyrosine kinase a promising target in cancer
therapy. … as EGFR inhibitors, offering promising avenues for further investigation in cancer …
therapy. … as EGFR inhibitors, offering promising avenues for further investigation in cancer …
Investigating new inhibitors with potential advantages for combating HER2-overexpressing head and neck squamous cancer cells; a practical and virtual screening …
138 天前 - … results showed, in accordance with our obtained docking result while the … inhibits
epidermal growth factor receptor (EGFR), is a molecular targeting agent for the treatment of …
epidermal growth factor receptor (EGFR), is a molecular targeting agent for the treatment of …
[HTML][HTML] Xie-Bai-San increases NSCLC cells sensitivity to gefitinib by inhibiting Beclin-1 mediated autophagosome formation
C Ma, X Zhang, X Mo, Y Yu, Z Xiao, J Wu, L Ding, C Lei… - Phytomedicine, 2024 - Elsevier
140 天前 - … to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), which
reduce treatment … a patient-derived xenograft (PDX) model with EGFR and PIK3CA mutations …
reduce treatment … a patient-derived xenograft (PDX) model with EGFR and PIK3CA mutations …
Identification of Novel EGFR Inhibitors for the Targeted Therapy of Colorectal Cancer Using Pharmacophore Modelling, Docking, Molecular Dynamic Simulation and …
A Krishnan K, S George Valavi… - Anti-Cancer Agents in …, 2024 - ingentaconnect.com
144 天前 - … One among those is Epidermal Growth Factor Receptor (EGFR), which is a … of
substituted 6-alkynyl-4anilinoquinazoline derivatives as potent EGFR inhibitors. Bioorg. …
substituted 6-alkynyl-4anilinoquinazoline derivatives as potent EGFR inhibitors. Bioorg. …
4 ″-Alkyl EGCG Derivatives Induce Cytoprotective Autophagy Response by Inhibiting EGFR in Glioblastoma Cells
146 天前 - … Epidermal growth factor receptor (EGFR)-targeted therapy has been proven vital
in the … Furthermore, we have found that EGFR inhibition with 4″-alkyl EGCG induces …
in the … Furthermore, we have found that EGFR inhibition with 4″-alkyl EGCG induces …