Epigenetic clock and methylation studies in vervet monkeys

AJ Jasinska, A Haghani, JA Zoller, CZ Li, A Arneson… - GeroScience, 2022 - Springer
DNA methylation-based biomarkers of aging have been developed for many mammals but
not yet for the vervet monkey (Chlorocebus sabaeus), which is a valuable non-human
primate model for biomedical studies. We generated novel DNA methylation data from
vervet cerebral cortex, blood, and liver using highly conserved mammalian CpGs
represented on a custom array (HorvathMammalMethylChip40). We present six DNA
methylation-based estimators of age: vervet multi-tissue epigenetic clock and tissue-specific …

[引用][C] Epigenetic clock and methylation studies in vervet monkeys. GeroScience 44, 699–717. 1469185x, 0

AJ Jasinska, A Haghani, JA Zoller, CZ Li, A Arneson… - 2022
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