过去一年中添加的文章,按日期排序

Mechanistic and Biological Perspectives on Erythropoiesis

EH Bresnick, T Papayannopoulou… - Experimental …, 2024 - exphem.org
5 天前 - epigenetic mechanisms governing cell fate transitions is transforming concepts on
how hematopoietic stem cells (HSCs) in the developing embryo and adult boneremodeling

Early B-Cell Factor 1: An Archetype for a Lineage-Restricted Transcription Factor Linking Development to Disease

M Sigvardsson - Transcription factors in blood cell development, 2024 - Springer
7 天前 - … This has been attributed to the ability of EBF1 to act as a pioneering factor with the
ability to remodel chromatin, thereby creating a B-lymphoid-specific epigenetic landscape. …

Molecular and functional interaction between autophagy and inflammasome in acute myeloid leukemia

BGS Macedo - teses.usp.br
12 天前 - … acquisition of multiple genetic and epigenetic alterations. The molecular alterations
that … and promote bone marrow tissue and biochemical architecture remodeling into a …

Sirt5 affects the metabolic remodeling of eosinophils by negatively regulating the level of succinylation modification of Pkm2 in eosinophilic chronic rhinosinusitis

SY Wu, BY Cai, ZW Cao, TY Wang… - World Journal of …, 2024 - Wiley Online Library
27 天前 - … In summary, this study focuses on the role of epigenetic regulation and its
potential mechanisms in the context of eCRS. The aim is to provide theoretical references for …

[HTML][HTML] Checkpoint inhibition in hematologic malignancies

JJ Pu, JJ Drabick, SE Prockop - Frontiers in Oncology, 2024 - ncbi.nlm.nih.gov
35 天前 - … in bone marrow infiltrating CD8+ and CD4+ T cells from 30 patients with acute
myeloid leukemia (AML) (Epigenetic … caused pathological chromatin remodeling. These data …

Trajectories in Cardiac Aging: Journey to the Crossroads of Inflammation and Metabolism

G Derumeaux, D Sawaki, G Czibik - Circulation, 2024 - Am Heart Assoc
37 天前 - Epigenetic alterations represent another sign of aging controlled by metabolism.
Epigenetic … Interestingly, epigenetic manipulation through miRNA modulators and histone …

Abstract A015: Exploiting endogenous replication stress with a novel targeted therapy in Ewing sarcoma

E Isenhart, A Gupta, B Gillard, K Attwood… - Molecular Cancer …, 2024 - AACR
44 天前 - … Finally, we utilize reduced representation bisulfite sequencing to examine the
epigenetic effects of these treatment regimens. Overall, the exploitation of high endogenous …

Novel epigenetic roles of lactylation in osteogenesis

K Sasa, T Kato, A Yamada - Epigenomics, 2024 - Taylor & Francis
55 天前 - Bone tissue is constantly undergoing a renewal process termed bone remodeling,
in which bone formation by osteoblasts and bone destruction by osteoclasts are repeated. …

Pathobiology of Pulmonary Arterial Hypertension

M Lewis, N Voelkel, F Kadri - Current Respiratory Medicine …, 2024 - ingentaconnect.com
85 天前 - … disease associated with occlusive pulmonary arterial remodeling of vessels < 500
μm for … Taken together in summary, multiple epigenetic modifications (which induce changes …

Novel Insights into the Links between N6-Methyladenosine and Regulated Cell Death in Musculoskeletal Diseases

J Han, C Wang, H Yang, J Luo, X Zhang, XA Zhang - Biomolecules, 2024 - mdpi.com
91 天前 - … Studies have shown that the epigenetic modulation of m6A influences mRNA pro…
the invasive and migratory of MM cells to bone remodeling capacity, thereby influencing the …