Epigenetics: regulation through repression
AP Wolffe, MA Matzke - science, 1999 - science.org
… have common molecular mechanisms that contribute to the epigenetic control of gene
expression (10). A key element in many epigenetic effects concerns the recognition of nucleic acid …
expression (10). A key element in many epigenetic effects concerns the recognition of nucleic acid …
The epigenetics of cancer etiology
AP Feinberg - Seminars in cancer biology, 2004 - Elsevier
… , imprinting errors, linked to changes in gene expression. While cancer family syndromes
have not been associated with epigenetic changes, a notable exception is Beckwith–…
have not been associated with epigenetic changes, a notable exception is Beckwith–…
[HTML][HTML] Genetic and epigenetic regulation of human lincRNA gene expression
… By investigating the epigenetic regulation of lincRNAs, we … DNA methylation and gene
expression (expression quantitative trait … in gene regulation are similar to protein-coding genes. …
expression (expression quantitative trait … in gene regulation are similar to protein-coding genes. …
Epigenetics and depression: return of the repressed
VS Dalton, E Kolshus, DM McLoughlin - Journal of affective disorders, 2014 - Elsevier
… Epigenetic modification of gene expression provides a … and the changes in gene expression
that are associated with … the future, epigenetic modifications of gene expression may provide …
that are associated with … the future, epigenetic modifications of gene expression may provide …
Nucleosome destabilization in the epigenetic regulation of gene expression
S Henikoff - Nature Reviews Genetics, 2008 - nature.com
… between nucleosome dynamics and epigenetic memory, and … configuration is crucial for
epigenetic inheritance. It now … is that epigenetic memory of gene expression is maintained …
epigenetic inheritance. It now … is that epigenetic memory of gene expression is maintained …
Lung cancer epigenetics and genetics
… for aberrantly-methylated genes utilizing the ability of 5-aza-2′-deoxycytidine to reactivate
gene expression of silenced genes in lung cancer cell lines. Expression profiles of cancer …
gene expression of silenced genes in lung cancer cell lines. Expression profiles of cancer …
[HTML][HTML] Molecular epigenetics and genetics in neuro-oncology
RP Nagarajan, JF Costello - Neurotherapeutics, 2009 - Elsevier
… of epigenetic control of gene expression in the development and function of the CNS. This
knowledge of the critical role of epigenetic … the role of epigenetic regulation in tumors arising …
knowledge of the critical role of epigenetic … the role of epigenetic regulation in tumors arising …
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
… that cause familial cancers when mutated in the germline; the selective advantage for
genetic and epigenetic dysfunction in these genes is very similar. The aberrant methylation can …
genetic and epigenetic dysfunction in these genes is very similar. The aberrant methylation can …
Epigenetics and metabolism
ST Keating, A El-Osta - Circulation research, 2015 - Am Heart Assoc
… For their ability to stably integrate metabolic information with gene expression, epigenetic
chromatin adaptations are increasingly appreciated in this phenomenon of metabolic memory. …
chromatin adaptations are increasingly appreciated in this phenomenon of metabolic memory. …
The role of epigenetics in genetic and environmental epidemiology
C Ladd-Acosta, MD Fallin - Epigenomics, 2016 - Taylor & Francis
… epigenetics in genetic and environmental epidemiology studies, provide a conceptual framework
when considering epigenetic … , gene expression of an exposure response gene may be …
when considering epigenetic … , gene expression of an exposure response gene may be …