过去一年中添加的文章,按日期排序

Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes

J Winkler, W Tan, CMM Diadhiou, CS McGinnis… - The Journal of Clinical …, 2024 - jci.org
2 天前 - … genes involved in epithelial-mesenchymal transition were upregulated in highly
metastatic tumors. We found that ITH was dominated by epithelial-mesenchymal plasticity (EMP…

[HTML][HTML] Factors Determining Epithelial-Mesenchymal Transition in Cancer Progression

P Tomecka, D Kunachowicz, J Górczyńska… - International Journal of …, 2024 - mdpi.com
19 天前 - … In this review, we have delved into the crucial role of EMT in cancer progression,
highlighting the importance of understanding the factors that regulate this process. We have …

Stemness and hybrid epithelialmesenchymal profiles guide peritoneal dissemination of malignant mesothelioma and pseudomyxoma peritonei

N Lazzari, G Rigotto, B Montini… - … Journal of Cancer, 2024 - Wiley Online Library
21 天前 - … This ability is mediated by the activation of a dynamic process, epithelialmesenchymal
plasticity (EMP), that promotes the survival of disseminated neoplastic cells in …

Catch me if you can: cellular plasticity in tumor progression and drug resistance

GL Rampioni Vinciguerra, I Segatto… - Frontiers in Cell and …, 2024 - frontiersin.org
29 天前 - … In human malignancies, cellular plasticity is aberrantly activated at all stages of
pre-malignant and malignant progression (Quintanal-Villalonga et al., 2020). This activation …

Epithelialmesenchymal plasticity in cancer: signaling pathways and therapeutic targets

X Wang, X Xue, M Pang, L Yu, J Qian, X Li, M Tian… - MedComm, 2024 - Wiley Online Library
35 天前 - … events including metastasis, … plasticity especially epithelialmesenchymal
plasticity (EMP). Tumor cells with EMP are manifest in three states as epithelialmesenchymal

IDDF2024-ABS-0280 FOLR1 promotes colorectal cancer plasticity and immune evasion via up-regulating STAT1, lactylation

S Chen, Q Liu, Q Yan - 2024 - gut.bmj.com
35 天前 - … to be up-regulated in CRC patients with poor prognosis. This research investigates
the mechanism by which FOLR1 promotes tumor plasticity and immune evasion in CRC. …

IGF1R signaling induces epithelial-mesenchymal plasticity via ITGAV in cutaneous carcinoma

M Lopez-Cerda, L Lorenzo-Sanz, V da Silva-Diz… - … & Clinical Cancer …, 2024 - Springer
38 天前 - … E/M cancer cells could be a risk factor for cSCC progression and tumor …
epithelial-mesenchymal plasticity (EMP) is key to blocking the generation of hybrid/mesenchymal …

[HTML][HTML] Natural product mediated mesenchymal–epithelial remodeling by covalently binding ENO1 to degrade m6A modified β-catenin mRNA

T Chen, G Liu, S Chen, F Zhang, S Ma, Y Bai… - … Pharmaceutica Sinica B, 2024 - Elsevier
53 天前 - … could inhibit the progression of HCC. Using high-throughput screening, chrysin
was selected from natural products to reverse epithelial-mesenchymal transition (EMT) by …

Intersecting Pathways: The Role of Hybrid E/M Cells and Circulating Tumor Cells in Cancer Metastasis and Drug Resistance

A Hariri, M Mirian, A Khosravi, A Zarepour… - Drug Resistance …, 2024 - Elsevier
53 天前 - … the epithelial-mesenchymal differentiation axis contribute to tumor heterogeneity.
Epithelial-mesenchymal plasticity … within a "plasticity window." Hari et al. (2020) reveal that this …

Breast Cancer Cells Exhibit Mesenchymal–Epithelial Plasticity Following Dynamic Modulation of Matrix Stiffness

CS Sankhe, JL Sacco, J Lawton, RA Fair… - Advanced …, 2024 - Wiley Online Library
59 天前 - … Overall, these findings reveal intermediate epithelial/mesenchymal states as cells
move … an important role for matrix mechanics in regulating mesenchymal–epithelial plasticity. …