[HTML][HTML] Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis
M Shimada, T Goshima, H Matsuo, Y Johmura… - Nature …, 2016 - nature.com
… in the culminated activation of Aurora B at centromeres, triggering activation of … Aurora
B-mediated H2AX-pS121 could provide a molecular scaffold for Aurora B autoactivation circuitry …
B-mediated H2AX-pS121 could provide a molecular scaffold for Aurora B autoactivation circuitry …
[HTML][HTML] Aurora B twists on histones for activation
M Shimada, M Nakanishi - Cell Cycle, 2016 - Taylor & Francis
… , we successfully demonstrate that H2AX-pS121 predominantly localizes at mitotic … results
indicate that Aurora B-mediated H2AX-pS121 facilitates Aurora B autoactivation circuitry at …
indicate that Aurora B-mediated H2AX-pS121 facilitates Aurora B autoactivation circuitry at …
[HTML][HTML] The ins and outs of Aurora B inner centromere localization
S Hindriksen, SMA Lens, MA Hadders - Frontiers in cell and …, 2017 - frontiersin.org
… The mitotic kinase Aurora B plays a crucial role in this … on Aurora B activity and thus involve
multiple feedback circuits. In … of the SAH affected Aurora B-mediated phosphorylation of outer …
multiple feedback circuits. In … of the SAH affected Aurora B-mediated phosphorylation of outer …
[HTML][HTML] Aurora B tension sensing mechanisms in the kinetochore ensure accurate chromosome segregation
SL McVey, JK Cosby, NJ Nannas - International Journal of Molecular …, 2021 - mdpi.com
… for translating mechanical force into Aurora B-mediated biochemical signals that regulate …
Aurora B regulates many aspects of mitosis [37], but it plays a critical role in sensing the tension…
Aurora B regulates many aspects of mitosis [37], but it plays a critical role in sensing the tension…
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis
… Our functional studies confirm the notion that Aurora B is critical for multiple aspects of mitotic
progression. Expression of the kinase-deficient mutant exerted a dominant-negative effect …
progression. Expression of the kinase-deficient mutant exerted a dominant-negative effect …
Priming chromatin for segregation: functional roles of mitotic histone modifications
ML Schmitz, JMG Higgins, M Seibert - Cell Cycle, 2020 - Taylor & Francis
… Centromeres play a crucial role during mitosis as they are hubs of … B auto-activation and
Haspin recruitment [Citation40]. After … In addition, Aurora B-mediated restriction of phosphatases …
Haspin recruitment [Citation40]. After … In addition, Aurora B-mediated restriction of phosphatases …
[HTML][HTML] Aurora kinases: novel therapy targets in cancers
A Tang, K Gao, L Chu, R Zhang, J Yang, J Zheng - Oncotarget, 2017 - ncbi.nlm.nih.gov
… C (AURKC), are essential kinases for cell division via regulating mitosis especially the …
physiological functions of Aurora kinases in mitosis, then describe the oncogenic role of Aurora …
physiological functions of Aurora kinases in mitosis, then describe the oncogenic role of Aurora …
γ-H2AX is present at mouse meiotic kinetochores
… In this study, we have analyzed the distribution of γ-H2AX during male mouse meiosis by
immunofluorescence on spread and squashed spermatocytes. We have found that γ-H2AX …
immunofluorescence on spread and squashed spermatocytes. We have found that γ-H2AX …
[HTML][HTML] Aurora kinases in ovarian cancer
JA Pérez-Fidalgo, V Gambardella, B Pineda… - ESMO open, 2020 - Elsevier
… Aurora kinases (AURK) are key regulators of the mitotic spindle formation. AURK is frequently
… Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis …
… Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis …
TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis
… factor EB) axis plays an essential role in this process through upregulating basal … autophagy
is summarized as a schematic (Fig. S7D). The essential role of FBXO22 in hormesis was …
is summarized as a schematic (Fig. S7D). The essential role of FBXO22 in hormesis was …