Establishment of a serum tumor marker for preclinical trials of mouse prostate cancer models

IV Huizen, G Wu, M Moussa, JL Chin, A Fenster… - Clinical cancer …, 2005 - AACR
Current prostate cancer research in both basic and preclinical trial studies employ
genetically engineered mouse models. However, unlike in human prostate cancer patients,
rodents have no counterpart of prostatic-specific antigen (PSA) for monitoring prostate
cancer initiation and progression. In this study, we established a mouse serum tumor marker
from a mouse homologue of human prostate secretory protein of 94 amino acids (PSP94).
Immunohistochemistry studies on different histologic grades from both transgenic and knock …

[PDF][PDF] Establishment of a Serum Tumor Marker for Preclinical Trials of Mouse Prostate Cancer Models

JC Lacefield, H Sakai, NM Greenberg, JW Xuan - researchgate.net
Current prostate cancer research in both basic and preclinical trial studies employ
genetically engineered mouse models. However, unlike in human prostate cancer patients,
rodents have no counterpart of prostatic-specific antigen (PSA) for monitoring prostate
cancer initiation and progression. In this study, we established a mouse serum tumor marker
from a mouse homologue of human prostate secretory protein of 94 amino acids (PSP94).
Immunohistochemistry studies on different histologic grades from both transgenic and knock …
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