The objective of this study is to investigate the effect of the interaction between salinity and plant growth regulators (Kinetin and gibberellin) on the salt tolerance of two bread wheat cultivars (Dijilla) and (Tamooze-2) under salinity conditions. The present study was conducted to assess the effects of Kinetin and gibberellin on plant dry matters (shoots and roots), chlorophyll content and stability in upper leaves, salt tolerance index, and organic contents in plant leaves of the two cultivars grown in salinized soils at two levels (0 and 16 ds/m). Seeds of both cultivars were sown in plastic pots which filled with the salinized soil in glass house during 2014-2015 sessions. Selected cultivar gave the highest dry matters, chlorophyll content and stability, and salt tolerance index under salinity condition as compared with local cultivar. Also the selected cultivar had the highest organic compounds in their leaves, especially under salinity condition. Both plant growth regulators were effective in increasing all the measured characters of both cultivars under non-saline condition but at salinity condition were effective in selected cultivar only. The Kinetin was more effective than the gibberellin in their effect on the salt tolerance of the plants under saline condition. Generally under these conditions the selected cultivar (Dijilla) was more salt tolerance than local cultivar.