Evaluation of analgesic and anti-inflammatory activities and molecular docking analysis of steroidal lactones from Datura stramonium L.

G Chandan, C Kumar, P Chibber, A Kumar, G Singh… - Phytomedicine, 2021 - Elsevier
Background Datura stramonium L. is widely used across the world for its therapeutic
potential to treat inflammatory disorders. The current work was designed to isolate and
identify steroidal lactones from D. stramonium leaves and evaluate their anti-inflammatory
and analgesic properties. Methods Several compounds were isolated from D. stramonium
leaves and characterized by nuclear magnetic resonance and high-resonance electron
spray ionization mass spectrometry techniques. Further, anti-inflammatory properties of …
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