Evaluation of optimal threshold of neutrophil-lymphocyte ratio and its association with survival outcomes among patients with head and neck cancer

SJ Ma, H Yu, M Khan, J Gill, S Santhosh… - JAMA Network …, 2022 - jamanetwork.com
Importance Given the role of inflammation in cancer progression, neutrophil-lymphocyte
ratio (NLR) from peripheral blood has been suggested as a readout of systemic
inflammation and a prognostic marker in several solid malignant neoplasms. However,
optimal threshold for NLR in US patients with head and neck cancer remains unclear.
Objective To evaluate the optimal NLR threshold as a potential prognostic biomarker for
survival outcomes. Design, Setting, and Participants This retrospective cohort study was …
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