Evidence of intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells
JR Mourant, AH Hielscher, AA Eick… - … Journal of the …, 1998 - Wiley Online Library
JR Mourant, AH Hielscher, AA Eick, TM Johnson, JP Freyer
Cancer Cytopathology: Interdisciplinary International Journal of …, 1998•Wiley Online LibraryBACKGROUND The objective of this study was to determine whether there are intrinsic
differences in the light scattering properties of tumorigenic and nontumorigenic cells from a
multistep carcinogenesis model. METHODS Wavelength‐dependent and polarization‐
dependent light scattering properties of cell suspensions were measured. RESULTS
Statistically significant differences were found between the tumorigenic and nontumorigenic
cells. CONCLUSIONS Differences in the light scattering properties of tumorigenic and …
differences in the light scattering properties of tumorigenic and nontumorigenic cells from a
multistep carcinogenesis model. METHODS Wavelength‐dependent and polarization‐
dependent light scattering properties of cell suspensions were measured. RESULTS
Statistically significant differences were found between the tumorigenic and nontumorigenic
cells. CONCLUSIONS Differences in the light scattering properties of tumorigenic and …
BACKGROUND
The objective of this study was to determine whether there are intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells from a multistep carcinogenesis model.
METHODS
Wavelength‐dependent and polarization‐dependent light scattering properties of cell suspensions were measured.
RESULTS
Statistically significant differences were found between the tumorigenic and nontumorigenic cells.
CONCLUSIONS
Differences in the light scattering properties of tumorigenic and nontumorigenic cells are attributed to a change in the average size of the scattering centers on the order of a few ten of nanometers. This work is relevant to the development of noninvasive optical methods for cancer diagnosis. Cancer (Cancer Cytopathol) 1998;84:366‐374. © 1998 American Cancer Society.
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