Exercise and skeletal muscle ageing: cellular and molecular mechanisms

A McArdle, A Vasilaki, M Jackson - Ageing research reviews, 2002 - Elsevier
As we age, our skeletal muscle becomes smaller and weaker. In addition, the remaining
muscle is more susceptible to damage, particularly following exercise, recovery from
damage is severely impaired and muscle is unable to adapt rapidly following sequential
periods of exercise. The mechanisms by which skeletal muscle damage occurs are poorly
understood and the role that an increased production of free radical species plays in this
damage is controversial. However, evidence is emerging which suggests that an increased …
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